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Unlocking the Secrets of Longevity Genes

A handful of genes that control the body's defenses during hard times can also dramatically improve health and prolong life in diverse organisms. Understanding how they work may reveal the keys to extending human life span while banishing diseases of old age

Resveratrol’s chemical structure gives it the ability to activate the sirtuin gene. This gene is important in suppressing DNA instability and allowing for repair of damaged DNA. One of the known causes of aging is the decreased ability for older cells to perfectly replicate DNA in every new cell. The build up of "DNA debris" in cells is connected to aging and the death of individual cells. Resveratrol increases the rate of deacetylation, which controls whether a gene is turned on or off. By controlling the rate of deacetylation and activating the sirtuin gene, resveratrol is demonstrated to have longevity effects
 

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